AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...

An evolutionarily conserved mechanism that regulates gene dosage "My lab started out studying dosage compensation in fruit flies, which is the process by which males with one X chromosome can achieve ...

Human females have two X chromosomes, and males only one. This chromosome imbalance also extends to other branches of the animal kingdom. Interestingly, the humble fruit fly has devised a different ...

Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light ...

Gene dosage mechanisms are required to maintain the expression of haploinsufficient genes properly, which, if misregulated, can lead to many developmental disorders. For the first time, researchers ...